The following anesthetic agents are known triggers of MH and are
not safe for use with (MH) Malignant Hyperthermia-susceptible patients:
The Drugs below can trigger MH
Inhaled General Anesthetics
Chloroform (Trichloromethane, Methyltrichloride)
Desflurane, Enflurane, Halothane, Isoflurane, Methoxyflurane, Sevoflurane, Trichloroethylene
The above MH triggering anesthetic gaseous drugs are the type administered when undergoing General Anesthesia.
Xenon (Rarely Used)
Depolarizing Muscle Relaxants Trigger MH
Succinylcholine (Suxamethonium) (SUX)
Succinylcholine is used to relax the tracheal muscles when placing a tube down the patients throat. (tracheal intubation.)
Resource: Malignant Hyperthermia Association of the United States
General Anesthesia
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Serious Reaction to General Anesthesia
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Anesthesia Q & A 10/2008
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General Anesthesia
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